Volume 5, Number 4 (volume 5, number 4 2013)                   IJDO 2013, 5(4): 151-156 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Azizi Soleiman F, Pahlavani N, Rasad H, Sadeghi O, Gohari M R. The Relationship between Inflammation, Oxidative Stress, and Metabolic Risk Factors in Type 2 Diabetic Patients. IJDO. 2013; 5 (4) :151-156
URL: http://ijdo.ssu.ac.ir/article-1-164-en.html

MS in nutrition science, Food Security Research Center, Department of Clinical Nutrition, Isfahan University of Medical Science, Isfahan, Iran.
Abstract:   (1154 Views)
Abstract Objective: Globally, 3-5.2 percent of people suffer from diabetes which is one of the most serious metabolic disorders resulting in an increase in inflammatory biomarkers e.g. interleukin-6, tumor necrosis factor-alpha, and C-reactive protein. The aim of this study was to investigate the relationship between inflammation, oxidative stress and fasting blood glucose, lipid profile and anthropometric parameters in patients with type 2 diabetes. Material and methods: This study was conducted as a cross-sectional study in Tehran through 2009-2010 on 45 men and women aged 35-65 years old with type 2 diabetes. Blood glucose, lipid profile, C-reactive protein, and malonedialdehyde were measured. Independent sample T-test and linear regression analysis were used. Results: Fasting blood glucose, malonedialdehyde, total cholesterol and body mass index were higher in women than in men but there was no difference between two sexes in other factors. Malonedialdehyde, neither directly nor after adjustment for sex was not related to fasting blood glucose, total cholesterol, triglycerides and anthropometric indices (weight, body mass index, and body fat mass). Conclusion: This study showed that oxidative stress had not any relationship with blood glucose, lipid profile, and anthropometric index, but inflammation was related to glycemia, body mass index, and fat mass. Control of inflammation and oxidative stress is necessary for accelerating treatment process and preventing complications due to them.
Full-Text [PDF 108 kb]   (525 Downloads)    
Type of Study: Research | Subject: Special
Received: 2014/10/4 | Accepted: 2014/10/4 | Published: 2014/10/4

Add your comments about this article : Your username or email:
Write the security code in the box

© 2015 All Rights Reserved | Iranian Journal of Diabetes and Obesity

Designed & Developed by : Yektaweb