دوره 6، شماره 4 - ( volume 6, number4 1393 )                   جلد 6 شماره 4 صفحات 163-167 | برگشت به فهرست نسخه ها


XML English Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Parsaeyan N, Rezvani M E. The Effect of Christ’s Thorn (Ziziphus Spina Christi) Leaves Extract on Lipid Profile, Lipid Peroxidation and Liver Enzymes of Diabetic Rats. IJDO. 2014; 6 (4) :163-167
URL: http://ijdo.ssu.ac.ir/article-1-210-fa.html
The Effect of Christ’s Thorn (Ziziphus Spina Christi) Leaves Extract on Lipid Profile, Lipid Peroxidation and Liver Enzymes of Diabetic Rats. دیابت و چاقی. 1393; 6 (4) :163-167

URL: http://ijdo.ssu.ac.ir/article-1-210-fa.html


چکیده:   (858 مشاهده)
Objective: The effect of herbal medicine is more useful than synthetic medicines. The present research paper aims to show the effects of leaves extracts of Zizyphus Spina Christi (ZSC) on lipid profile, lipid peroxidation and activities of aminotransferase enzymes in streptozocin induced diabetic adult male rats. Materials and Methods: Fifty six male rats weighing 150-200 gm were included in this study. They were divided into 8 groups. The first group, non-diabetic control rats received distilled water. The second, third and fourth groups, non-diabetic rats were given doses 50 mg/kg body weight (BW), 75 mg/kg (BW) and 100mg/kg (BW) ZSC extracts. The fifth group, diabetic control, received distilled water. The sixth, seventh and eighth were given doses, 50mg/kg (BW), 75 mg/kg (BW) and 100mg/kg (BW) ZSC extracts. Weight and fasting blood glucose were measured every week and the period of treatment continued for four weeks. Serum lipid profile, malondialdehyde (MDA) and aminotransferase enzymes (AST, ALT) were measured at the end of experiment. Results: In diabetic rats ZSC leaves extract significantly reduced serum total cholesterol, triglyceride, LDL-C, AST (aspartate aminotransferase) and ALT (alanine aminotranferase) (P<0.05). The serum malondialdehyde markedly decreased (P<0.001), But HDL –C increased significantly (P<0.05). Conclusion: The present paper revealed that ZCS leaves extract has beneficial effects on lipid profile, lipid peroxidation and aminotranferase enzymes in diabetic rats.
متن کامل [PDF 93 kb]   (836 دریافت)    
نوع مطالعه: پژوهشي | موضوع مقاله: تخصصي
دریافت: ۱۳۹۴/۷/۶ | پذیرش: ۱۳۹۴/۷/۶ | انتشار: ۱۳۹۴/۷/۶

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
کد امنیتی را در کادر بنویسید

کلیه حقوق این وب سایت متعلق به مجله ایرانی دیابت و چاقی می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2015 All Rights Reserved | Iranian Journal of Diabetes and Obesity

Designed & Developed by : Yektaweb