Objective: The risk of cardiac death in diabetic patients is 3 times more than non-diabetics. But it is not determined who need cardiac screening. About 41% of diabetic patients with silent ischemia are missed. the carotid intima-media thickness (CIMT) and ankel brachial index are two independent,simple and non invasive method in vascular complications diagnosis in diabetic patients.The aim of this study was to evaluate the assosiation of CIMT and ABI in prediction of silent myocardial ischemia in myocardial perfusion scintigraphy in Asymtomatic diabetic papulation.

Materials and Methods: This was an analytic cross-sectional study. The convenient sampling was used. About 114 patients with diabetics and no history and symptom of coronary artery disease (CAD) were included. Myocardial perfusion scan (MPI), CIMT and ABI were done. All of statistical analysis was done by SPSS-20.

Results: Totally114 diabetic patients without cronary artery disease symptoms were included .About 66.7% were female. The mean age of patients was 53.8± 8.6 years old. About 50% (57) of patients were normal. The mean of CIMT was 0.93 ± 0.21 and mean ABI was 0.97 ± 0.11. Regarding the anlysis of variance (ANOVA) there were significant differences of mean CIMT and ABI between normal and moderate to severe ischemia in MPI.

Conclusion: Our findings showed that CIMT and ABI is significantly different between patients with and without ischemia. The CIMT and ABI are simple, non-invasive, and inexpensive tests that may be used to identify individuals who are at high risk of developing cardiovascular disease (diabetic patients).