Objective: Gestational diabetes mellitus (GDM) is the most common metabolic disorder during pregnancy. This study aimed to compare the prevalence of GDM positive screening tests with Fasting Blood Sugar (FBS) and Glucose Challenge Test (GCT) in pregnant women without risk factors in Esfarayn, Iran.
Materials and Methods: This descriptive study was conducted on 997 pregnant women, who were referred to the health Center 2 in Esfarayen city in 2014-2015. The sampling method was convenient.  It should be noticed that all of pregnant women did not have risk factor of GDM.
Results: 997 pregnant women prenatal care had a fasting glucose test among them, 4 patients had abnormal FBS, While 40 of them after GCT had blood glucose greater than 140 mg and, 20 cases in 1 and 2-hour GCT at the same time had high blood glucose. Conclusion: Result of our study showed that glucose challenge test for GDM screening is worthwhile, FBS, alone is not useful to screen for GDM

Keywords: Gestational diabetes, Glucose tolerance test, Glucose challenge test, Fasting blood sugar

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