دوره 4، شماره 3 - ( 6-1391 )                   جلد 4 شماره 3 صفحات 120-126 | برگشت به فهرست نسخه ها


XML English Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Azizian H, Ebrahim Rezvani M, Esmaeilidehaj M, Bagheri S M. Anti-Obesity, Fat Lowering and Liver Steatosis Protective Effects of Ferula asafoetida Gum in Type 2 Diabetic Rats: Possible Involvement of Leptin. IJDO. 2012; 4 (3) :120-126
URL: http://ijdo.ssu.ac.ir/article-1-94-fa.html
Anti-Obesity, Fat Lowering and Liver Steatosis Protective Effects of Ferula asafoetida Gum in Type 2 Diabetic Rats: Possible Involvement of Leptin. دیابت و چاقی. 1391; 4 (3) :120-126

URL: http://ijdo.ssu.ac.ir/article-1-94-fa.html


چکیده:   (3209 مشاهده)
Objective: Control of weight gain is an important strategy in reducing the diabetes incidence. Recently, herbal drugs have been used as a complementary and alternative medicinal care. This study was conducted to determine the effect of Ferula asafoetida on weight gain, fat accumulation, liver steatosis and leptin level. Materials and Methods: All rats of control and treatment groups received daily tap water (P.O) as vehicle mixed with fructose 10%. Two treatment groups received FAF oleo-gum resin at doses of 25 or 50 mg/kg (P.O). Normal rats received only tap water and standard chow food. Body weights, abdominal fat, size of epididymal adipocyte and serum leptin were recorded. Result: Administration of Ferula asafoetida significantly decreased body weights, abdominal fat and size of epididymal adipocyte compared to untreated rats (P<0.05). Levels of serum leptin were significantly decreased in treated rats (P<0.05). Conclusion: This study showed that Ferula asafoetida extract has anti-obesity, fat lowering effects and can prevent liver steatosis in type 2 diabetic rats. Reduction of serum leptin is associated with protective effects of Ferula asafoetida in obese diabetic rats.
متن کامل [PDF 146 kb]   (951 دریافت)    
نوع مطالعه: پژوهشي | موضوع مقاله: عمومى
دریافت: ۱۳۹۲/۳/۲۸

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
کد امنیتی را در کادر بنویسید

کلیه حقوق این وب سایت متعلق به مجله ایرانی دیابت و چاقی می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2015 All Rights Reserved | Iranian Journal of Diabetes and Obesity

Designed & Developed by : Yektaweb