Iranian Journal of Diabetes and Obesity

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Objective: There are association between oxidative stress and incidence of some chronic diseases, such as type 2 diabetes mellitus (T2DM). Food containing antioxidant compounds, such as some spices, are the natural ways to deal with oxidative stress. The purpose of this study was to determine the effect of sumac powder (Rhus coriaria L) on the glycemic profile in patients with T2DM.
Materials and Methods: In this experimental study, 60 T2DM patients were selected and randomly divided into two groups: intervention and control groups. The intervention group received 2 packs of 3 grams sumac powder once a day for 3 months in two bowls of low-fat yoghurt for lunch and dinner and the control group received two bowls of low-fat sumac-free yoghurt  for lunch and dinner. Data collection was performed by a checklist at the beginning and end of the study and blood samples were collected. Data were analyzed using paired T-test and independent t-test. The significance level was considered at P<0.05.
Results: In this study, the fasting serum insulin levels decreased in the intervention group. But the mean changes of variables were not statistically significant between two groups. There was also no difference in other factors between the beginning and end of the study.
Discussion: This study showed that daily intake of 6 grams sumac powder for three months had no significant effect on the glycemic profile (fasting blood sugar and 2-hours post-prandial glucose and glycosylated hemoglobin A1C) and serum insulin levels of diabetic patients.

 

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Objective: Resistance exercise is recommended as effective treatments for people with type 2 diabetes. However, the impact of this mode of exercise on blood glucose, insulin and insulin resistance in Iranian's type 2 diabetic patients is unclear. We conducted a systematic review of the literature for the effect of resistance exercise training on these clinical markers in Iranian's type 2 diabetic patients.
Materials and Methods: Electronic databases including Sid.ir, magiran.com, PubMed, Google scholar, Embase, Medline and science direct were investigated and searched for persian and english articles, published before July 2017, which performed in Iran. Standardized mean difference (SMD) with a 95% confidence interval (CI) was calculated to assess this association. Of 99 articles retrieved, 9 met our inclusion criteria and were included in the meta-analysis model. Data analysis were done using STATA software version 12.0 and P≤0.05 was set as statistical significant.
Results: The results indicate that there were significant association between resistance training and blood glucose levels (P=0.0001; -1.367,-0.756; 95%CI), insulin (P=0.0001;-0.904,-0.313; 95%CI) and insulin resistance (P=0.0001;-1.006,-0.366; 95%CI).
Conclusion: This meta-analysis showed that resistance exercise training program in patients with type 2 diabetes has a significant effect on glycemic control. It is recommended that sport and medicine experts use resistance exercise as a non- pharmacological intervention for treatment of type 2 diabetes patients. Future long term studies focusing on patient-relevant outcomes are warranted.
 

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Objective: Diabetes is one of the chronic diseases which can be accompanied with suicide. The study was conducted to assess and compare the prevalence of suicidal ideation in diabetic patients receiving insulin and oralmedication treatment.
Materials and Methods: In this cross-sectional study, 2000 patients with diabetes supported by diabetes institute of Rafsanjan in 2017. After giving conscious permission, the patients filled in a demographic checklist and Beck suicidal ideation questionnaire. The data were analyzed using SPSS-16.
Results: Prevalence of suicidal ideation in patients with diabetes receiving insulin was 3.2% (n=32) and in people receivingoral medication treatment was 3.1% (n=31). There were no association between suicidal ideation and the method of diabetes treatment. Suicidal ideation was more prevalent in illiterate people; however, no significant relationship was seen between suicidal ideation and education level. Also, there was no significant relationship between marital status and suicidal ideation. There was no relationship between suicidal thoughts and the method of treatment (P-value: 0.05).
Conclusion: Suicidal ideation is more prevalent in diabetic patients, but there were not differences between two group under insulin therapy and oral anti-diabetic agents.

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Objective: The role of post-exercise on the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) is not evident in pediatrics with type 1 diabetes (T1D) yet. This paper reports the results of a research study on how concurrent exercise training affects NLR and PLR in children with T1D.
Materials and Methods: In this randomized controlled trial, 40 children (boys and girls aged 11.11 ±2.29 years) were randomly divided into an experimental (n=20) and a control group (n=20). The training program included concurrent resistance-aerobic training, which was intermittently performed for 60 minutes at a rate of three times a week for 16 weeks. The participants were analyzed for blood glucose homeostasis, NLR and PLR before and after the program. Data were analyzed by SPSS 22 software with paired T-test and covariance analysis (P< 0.05).
Results: The results showed that PLR significantly (P= 0.002) decreased in the exercise group after 16 weeks of concurrent training. This significance was observed between the groups too (P= 0.003). HbA1c decreased both in the exercise group and between the groups (P= 0.001, P= 0.003). NLR exhibited a significant increase both in the exercise group (P= 0.021( and between the groups )P= 0.012(.
Conclusion: Concurrent exercise training reduces PLR and HbA1c in children with T1D, which may be related to the anti-inflammatory effects of exercise training.