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Showing 4 results for Lotfi

Shima Dehghan Banadaki, Hassan Mozaffari-Khosravi, Sedighe Ahmadi, Mohammad Kazem Hajimirzadeh, Mohammad Hassan Lotfi,
Volume 6, Issue 4 (volume 6, number4 2014)

Objectives: Inflammation is a common complication in patients treated with hemodialysis and increasing in inflammatory factors such as C-reactive Protein (CRP) is associated with increased cardiovascular disease and mortality in these patients. The purpose of this study was to investigate the effect of oral L- carnitine supplementation on serum CRP concentration and fasting blood sugar (FBS) in patients undergoing hemodialysis. Materials and Methods: This study was a randomized clinical trial on 50 patients (30 males and 20 females) undergoing hemodialysis in the age range of 21-84 years from hemodialysis units of Yazd hospitals. Participants randomly divided into two groups, the Carnitine group (CaG) consumed daily oral syrup of L- carnitine containing 1000 mg of Carnitine for three months and the control group (CoG) did not use Carnitine. Serum levels of CRP and FBS were measured at baseline and at the end of the intervention. Statistical analysis was performed using the SPSS version 16.0. Results: the mean difference in CRP concentration in CaG and CoG were, 1.95 ±9.4 and 0.6±10.8 (μg/l), respectively (P-value=0.7) and the mean of FBS at the baseline and after 12 weeks in the CaG were 118.7±51.4 mg/dl and 110.1±48.2 mg/dl, respectively (P-value=0.3) and in the CoG were 142.8±88.7 mg/dl and 131.8±68.9 mg/dl (P-value=0.26). Conclusion: The oral administration of daily 1000 mg of L-carnitine for three months doesn’t effect on serum CRP and FBS concentrations in patients undergoing hemodialysis.
Fatemeh Alizadeh, Mohammad Amin Lotfi, Fariba Sepehri, Mostafa Saberi, Reza Bidaki, Parisa Balaei, Mohammad Hossein Ahmadie,
Volume 8, Issue 2 (volume 8, number 2 2016)

Objective: Suicide is seen in major depression, also in chronic diseases patients. HbA1C is a marker of long-term control of diabetes. The aim of this study was evaluation of the suicidal ideations in diabetic patients and its association with the status of blood sugar control based on Hemoglobin A1c (Hb A1c).

Materials and Methods: This study is a cross-sectional study. The patients were selected randomly. In this study, 180 diabetic patients were studied who were referred to the Ali Ibn Abitaleb Hospital Diabetes Center in Rafsanjan. This study data contain three categories, including demographic, Beck Depression Inventory, Beck suicidal ideations Inventory. HbA1c was extracted from the patients file. The software SPSS-17 was used. The t-test, ANOVA, Chi square and correlation coefficient tests were used.

Results About %36.7 of the patients were male and 114 (%63.3) were female. The mean (± SD) age of patients was 14.28(± 56.98) years (range: 14 - 88 years). Of these patients, 66 (%36.7) reported a history of depression and 114 (%63.3) no depression history. The mean of diabetes duration was 9.25±6.15 years. The mean (± SD) of HbA1c level was 2.08 ± 8.4 (range: 4.8-19.6).

Conclusion: Generally our findings showed that the prevalence of suicidal ideation in the diabetic population in Rafsanjan is less than the general population and other studies. There is no significant relationship between suicidal ideation and the age, sex, duration of diabetes, HbA1c levels, and history of depression.

Narjes Hazar, Majid Jafarizadeh Malamiri, Mohsen Mirzaei, Foroozandeh Kalantari, Mohammad Reza Sadeghiantafti, Mohammad Hassan Lotfi, Ali Zare, Masoud Rahmanian,
Volume 9, Issue 4 (volume 9, number 4 2017)

Objective: Gestational Diabetes Mellitus (GDM) is an important condition in diabetes categories causing significant complications including pre-eclampsia and eclampsia among pregnant women. The aim of this study was to estimate the trend of annual GDM incidence and its risk factors in Yazd province, Iran, from 2008 to 2013.
Materials and Methods: The present study was conducted as a prospective cohort study in which all pregnant women who had attended primary health care centers were screened for GDM. Annual GDM incidence was calculated for all and also according to 5-year age groups and residential area (urban/rural). Secular trends for GDM incidence and its risk factors were also evaluated.
Results: In this study, 67320 pregnant women were screened for GDM and 5425 pregnant women were diagnosed as GDM with 6-year incidence of 8,6%. Annual incidence of GDM increased from 3.1% in 2008 to 18.9% in 2013. Assessment of crude and age-adjusted incidence across the years of follow up revealed incremental secular trend (P-value<0.001). Changes in GDM risk factors including maternal age and family history of diabetes were also significantly positive. GDM incidence increased in both rural and urban areas but the observed trend slopes were opposite in these different contexts.
Conclusion: Clinicians should have specific regard to pregnant women with some risk factors for timely diagnosis and treatment. Meanwhile returning to previous life style of rural area can help to decrease GDM incidence. 

Farzad Nazem, Salman Lotfi,
Volume 12, Issue 4 (volume 12, number 4 2020)

Objective: Obesity is a medical problem that increases the risk of health problems like diabetes. Hormones secreting from fat tissue, Leptin, are correlated with body mass index. Leptin reduces the person's appetite by acting on specific centers of their brain to reduce their urge to eat. And insulin, a hormone produced by the pancreas, is essential for regulating carbohydrates and the metabolism of fat. A positive relationship between leptin levels and insulin resistance in children showing in this study is to determine the effect of continues-endurance and interval-endurance on leptin serum levels and insulin resistance in over-weighted youths.
Materials and Methods: This study is a semi-experimental design. Thirty boys were voluntarily selected as a matched two experimental groups and a control. Physical profiles included aged 16-19, BMI; 37.75 (±4.46) KG/M2, base functional capacity: 32.8 (±3.6) ml/kg/min which dividing by three equal groups: the submaximal training interval, a continuum and interval and control group performed the submaximal running program for six weeks on 3 D/W. The selected parameters were evaluated for an intervention pre and post-conditions.
Results: weight and body mass index variables were decreased by about 2.5-3% after exercise intervention. Plasmatic leptin levels were reduced by about 45% in the continuum and interval control groups. HOMA-IR & QUICKI indexes altered in the EG (8.9 %, 7.8%) (P-value < 0.05).
Conclusion: Presumably, 2 exercise program patterns lower than lactate threshold could change body composition profile, basal leptin level, and blood glucose /insulin concentrations, which probably induced changes in resistance to insulin.

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