Iranian Journal of Diabetes and Obesity

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Objective: Lack of exercise is the fourth cause of death in the world. There is an inverse relationship between physical activity and the risk of diabetes. The aim of this study was to determine physical activity status and its related factors among type 2 diabetic patients in Hamadan, west of Iran. Materials and Methods: This analytical-observational study was performed on320 type 2 diabetic patients recruited with a convenient sampling method. The participants completed a self-administered checklist including demographic characteristics, International Physical Activity Questionnaire (IPAQ) and psychological factor such as Knowledge, attitudes and self-efficacy. Data analysis was done with the SPSS software (version 16), using, one way ANOVA, chi-square tests and Fisher's exact test. Results: Physical activity of most patients (57.5%) was moderate. The associations between physical activity and age, education, occupation and marital status were significant (P<0.05). One way ANOVA indicated that attitude and self-efficacy were significantly associated with physical activity. Conclusion: The demographic and psychological variables relationship with physical activity is important. These findings can be used as an introduction to design effective intervention to promote physical activity.

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Abstract

Objective: Diabetes is now known as one of the chronic diseases that besides body have negative effects on the psychological status of patients and it is one of the predisposition diseases which can lead to opportunistic infection like pathogens parasites. The aim of present study was Frequency distribution of intestinal parasitic infections in diabetic patients – in Yazd.

Materials and Methods: This descriptive and cross sectional study was performed on 500 stool samples of Diabetic patients and healthy individuals with cluster random sampling in Yazd diabetes research centers from December 2012 to December 2013. Stool samples were collected, fixed and examined by Formalin- ether method (FEM) for detecting pathogen.

Results: In this study 500 stool samples [250 (92 men and 158 women) from control and 250 (91 men and 159 women) from diabetic patients] were collected. The results of this study indicated that intestinal parasites rate in diabetic patients is higher (61:24.4%) than healthy control group (58:23.2%).

Conclusion: The results showed a high prevalence of risk factors for diabetes complications and intestinal parasitic. Due to in Immunocompromised patients, it need for establishment of Diagnostic methods are emphasized.

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Objective: Exercise and herbs can possess synergistic effects to control diabetes side-effects. The purpose of the present study was to investigate the effects of high intensity interval training (HIIT) and curcumin supplement on activity levels of superoxide dismutase (SOD) and catalase of heart tissue in diabetic rats.
Materials and Methods: Thirty-two male Wistar rats were randomly divided in to four groups of curcumin, training-placebo, training-curcumin and control. The subjects were trained to do HIIT on treadmill and in the fashion of increasing manner. Diabetes was induced via injection of 50 (ml/Kg rat weight) STZ. Fifty (ml/kg rat weight) curcumin was nourished to the animals of the curcumin groups, by using the gavage technique during eight weeks (five days a week). The rats were anesthetized via intraperitoneal injection of ketamine, 24 hrs after the intervention. Then heart tissues were separated from bodies of the rats to examine changes in SOD and catalase enzymes.
Results: Activity levels of SOD and CAT enzymes of the three groups of curcumin, training-placebo, and training-curcumin increased significantly more than control group. But no significant difference was observed between those first three groups (P≤0.05).
Discussion: The results of the present study indicated that either HIIT or taking curcumin supplement could solely contribute significant enhancement to activity levels of antioxidant enzymes within heart tissues of diabetic mice. Though, those two interventions would not strengthen the influences of each other.

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Objective: It was reported exercise and herbal medicine can possess synergistic effects to control of diabetes complications. The purpose of the present study was investigation of the effects of high-intensity interval training (HIIT) and taking curcumin supplement on activity levels of GPX and MDA of heart tissue in diabetic rats.
Materials and Methods: Thirty-two male Wistar rats were randomly divided to four groups of curcumin, training-placebo, training-curcumin, and control. The subjects had being trained to perform HIIT on treadmill and in the fashion of increasing manner. Diabetes was induced via injection of 50 (ml/Kg rat weight) STZ. Fifty (ml/kg rat weight) curcumin had being nourished to the animals of the curcumin groups, by using the gavage technique, during a period of eight weeks (five days a week). The rats were anesthetized via intraperitoneal injection of ketamine, 24 hours after the intervention. Then, heart tissues were separated from bodies of the rats to examine changes in GPX and MDA enzymes.
Results: Activity levels of GPX enzyme of the three groups of curcumin, training-placebo, and training-curcumin increased significantly than correspondent levels of the control group. Activity levels of MDA enzyme of the three groups of curcumin, training-placebo, and training-curcumin decreased significantly than correspondent levels of the control group. Though, no significant difference was observed between those first three groups (P-value≤0.05).
Discussion: The findings indicated that either HIIT or taking curcumin supplement or combination of both could solely contribute significant enhancement to activity levels of antioxidant enzymes and decreasing of Oxidative enzymes within heart tissues of diabetic mice. Although, those two interventions would not strengthen the influences of each other in decrease of MDA but they would strengthen the influences of each other in increasing of GPX.

 

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Objective: The purpose of this study was to investigate the effect of exercise training and curcumin supplementation combination on the lipid profile of inactive middle-aged men.
Materials and Methods: This is an experimental study. The studied population was middle-aged men who were categorized as inactive. The mean (± standard deviation) age of participants was 34/82 (±6.54). They were 60 volunteers who were assigned to four groups by simple randomization, including the training group (N = 15), the training-curcumin group (N = 15), the curcumin group (N = 15), and the control group (N = 15).Three training sessions were carried out weekly for eight consecutive weeks, including weight training and running on a treadmill with 65 percent of maximum oxygen consumption for the training group. The curcumin was administered as 80 mg gelatin capsule 5 days in a week for eight consecutive weeks. Twenty-four hours before the first session and 48 hours after the last session, blood samples were taken and transferred to the laboratory. The statistical analyses were done via SPSS Software (Version 22).
Results: There was a significant difference between the interactive effects of eight weeks of combined exercise training and supplementation of curcumin on triglyceride and plasma high density lipoprotein (HDL) (P-value: 0.008 and 0.002), but their effect on low density lipoprotein (LDL) and cholesterol was not significant (P-value: 0.06 and 0.42). Moreover, there was a significant difference between cholesterol, LDL, HDL and triglyceride in the pre-test and post-test.
Conclusion: Combined exercise trainings and curcumin extract can be used to improve the lipid profile of inactive middle aged people.

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Objective: Low physical activity is the fourth risk factor of death worldwide. Approximately 27% risk of diabetes is reduced by 150 minutes of moderate physical activity per week. The present study was designed to determine the predictors of physical activity promotion among type 2 diabetic patients.
Materials and Methods: In this cross sectional study 320 patients with type 2 diabetes were included. The data collection tool was a questionnaire, consisting of three main parts; demographic characteristics, International Physical Activity Questionnaire (IPAQ) and Theory of Planned Behavior (TPB) theoretical constructs. Statistical software package SPSS (SPSS Inc version 20) used for all statistical analyses. To determine physical activity and predictive factors a series of logistic regression and bivariate correlations and descriptive analysis were computed.
Results: About 57.5% of patients had moderate levels of physical activity. Significant positive correlation between subjective norms and attitudes toward behavior (P-value= .0001) was seen. Significant positive correlations between behavioral intention and attitude toward the behavior (P-value= .0001) and subjective norms (P-value= .0001) was observed.
Conclusion: The results of the present study showed TPB based physical activity and demographic variable have key role in diabetic patient physical activity levels. To promote physical activity these findings can be used to design effective interventions