Iranian Journal of Diabetes and Obesity

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Abstract

Objective: Obesity is related to anemia which is explained its mechanism as disorder in iron absorption but the more rational reason is anemia of inflammation or anemia of chronic disease. The aim of this study was to define the prevalence of obesity in patients with normochromic normocytic anemia.

Materials and methods: We screened 406 patients who were referred to endocrine clinic. They were excluded from study if suffering from malignancy, hypo or hyperthyroidism, diabetes, growth hormone disorder, rheumatologic disorder or corticosteroid consumption. The complete blood count were checked in each participants. The patients with normochromic, normocytic anemia were diagnosed. Data was analyzed by SPSS17 software.

Results: Among this population, 26 persons had normochromic, normocytic anemia and 11 (42.3%) patients had central obesity. In remainder of persons (Without normochromic, normocytic anemia), 58.4% had central obesity.Overall, 49 patients had anemia and central obesity together. About 53% of them had normochromic normocytic anemia.

Conclusion: Central obesity is a common and complex phenomenon which is due to multiple etiologies. But based on our study, although the prevalence of central obesity was lower in patients with normochromic normocytic anemia, in 42.3% of them there was no source of inflammation except central obesity. Most patients with anemia and central obesity had normochromic normocytic anemia.

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Objective: Obesity is a medical problem that increases the risk of health problems like diabetes. Hormones secreting from fat tissue, Leptin, are correlated with body mass index. Leptin reduces the person's appetite by acting on specific centers of their brain to reduce their urge to eat. And insulin, a hormone produced by the pancreas, is essential for regulating carbohydrates and the metabolism of fat. A positive relationship between leptin levels and insulin resistance in children showing in this study is to determine the effect of continues-endurance and interval-endurance on leptin serum levels and insulin resistance in over-weighted youths.
Materials and Methods: This study is a semi-experimental design. Thirty boys were voluntarily selected as a matched two experimental groups and a control. Physical profiles included aged 16-19, BMI; 37.75 (±4.46) KG/M², base functional capacity: 32.8 (±3.6) ml/kg/min which dividing by three equal groups: the submaximal training interval, a continuum and interval and control group performed the submaximal running program for six weeks on 3 D/W. The selected parameters were evaluated for an intervention pre and post-conditions.
Results: weight and body mass index variables were decreased by about 2.5-3% after exercise intervention. Plasmatic leptin levels were reduced by about 45% in the continuum and interval control groups. HOMA-IR & QUICKI indexes altered in the EG (8.9 %, 7.8%) (P-value < 0.05).
Conclusion: Presumably, 2 exercise program patterns lower than lactate threshold could change body composition profile, basal leptin level, and blood glucose /insulin concentrations, which probably induced changes in resistance to insulin.