Amir Taghipour Asrami, Hadi Ghaedi, Ebrahim Banitalebi,
Volume 10, Issue 4 (10-2018)
Abstract
Objective: Physical exercise is a well-established therapeutic method in type 2 diabetes treatment. The purpose of this study was to investigate the effects of eight weeks combined and High Intensity Interval Training on serum apelin levels and pancreatic β-cell function in overweight women with type 2 diabetes mellitus.
Materials and Methods: Fifty-two overweight female patients with type 2 diabetes (aged 45-60 years old, BMI> 30) with HbA1c>6.5% participated in the study voluntarily. The participants were assigned to High Intensity Interval Training (HIIT) group (n= 17), combined training group (n= 17), and control group (n= 18) according to their HbA1c levels. The exercises included 12 weeks of combined training and HIIT. Levels of HbA1c and fasting glucose and insulin were measured.
Results: There was a significant decrease in the fasting blood glucose in the HIIT groups (P-value: 0.001). Serum insulin levels showed significant increases in the HIIT (P-value: 0.001) and combined training groups (P-value: 0.001). Changes in apelin level were not significantly different within HIIT and combined training groups (P-value: 0.13 and 0.09, respectively). The data showed significant differences in pancreatic β-cells function in HIIT (P < 0.001) and combined training groups (P= 0.003). Furthermore, the ANCOVA test showed that there were no significant differences in fasting blood glucose concentrations (F= 1.853, P-value: 0.171), apelin (F= 0.511, P-value: 0.12). However, significant differences were observed between groups in insulin (F= 3.622, P-value: 0.036), and β-cell function (F= 4.243, P-value: 0.003).
Conclusion: Physical exercise is an effective training method to improve glycemic control in woman with type 2 diabetes.
Masomeh Sarmadiyan, Davood Khorshidi, Mohammad Karimi,
Volume 11, Issue 4 (12-2019)
Abstract
Objective: Menopause is a normal biological process associated with hormonal and metabolic changes. The purpose of this study was to investigate the effect of combined training on estradiol levels and some metabolic risk factors in obese and overweight postmenopausal women.
Materials and Methods: In this quasi-experimental study, 24 postmenopausal women were randomly divided into experimental and control groups. Subjects of experimental group were performed 10 weeks of combined training including resistance and aerobic exercises. Control group did not participate in any exercise training. Fasting glucose, insulin, estradiol, HOMA-IR and body fat percentage measured at the beginning and after training.
Results: There were no significant differences in estradiol (P-value: 0.87), glucose (P-value: 0.09), insulin (P-value: 0.11), HOMA-IR (P-value: 0.08) and body fat percentage (P-value: 0.24) between experimental and control groups after combined exercise training.
Conclusion: This study showed that 10 weeks of moderate-intensity combined exercise training has no effect on serum estradiol level and insulin resistance in overweight/obese postmenopausal women.
