en عمومى General پژوهشي Research BACKGROUND: The aim of this study was to determine the prevalence and risk factors of the sensory neuropathy in type 2 diabetic patients referring to Yazd Diabetes Research Center. Neuropathy is one of the most common complications of both type 1 and type 2 diabetes melli-tus. MATERIAL AND METHODS: This is a cross-sectional study on 2350 diabetic patients (1071 male, 1279 female) referred to Yazd Diabetes Research Center (Iran) from June 2007 to February 2008. Data collection was carried out through a questionnaire including demographic subject, duration, body weight and length, lab test (HbA1c, 2hpp, FBS), Body Mass Index (BMI). Blood Pressure was measured on the right arm after a five-min rest. Neuropathy was confirmed using a Semmes Weinstein 10 g monofilament over 10 areas of the feet, ankle reflexes and vibration over the great toe and ankle. RESULTS: The prevalence of type 2 diabetes and diabetic sensory neuropathy in Yazd province is 14.5% and 51.7%, respectively. The prevalence of sensory neuropathy in male was 49.9% and 53.2 % in female, that increased by age (P = 0.001), duration of diabetes (P = 0.001), HbA1c (P = 0.001) and poor glycemic control (high FBS and 2hpp). CONCLUSION: Age, duration of diabetes, HbA1c and poor glycemic control were considered to be the risk factors for sensory neuropathy Type 2 diabetes mellitus, prevalence, sensory neuropathy. 30 35 http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-3-15&slc_lang=en&sid=1 Abolghasem Rahimdel No Mohammad Afkhami-Ardekani Yes Amin Souzani No Mojgan Modaresi No Mohammad Reza Mashahiri No