Iranian Journal of Diabetes and Obesity
IJDO
Medical Sciences
http://ijdo.ssu.ac.ir
1
admin
2008-6792
2345-2250
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8888
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en
jalali
1394
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gregorian
2015
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online
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fulltext
en
The Effect of Magnesium and Zinc on Glycemic Control in Type 2 Diabetic Patients
تخصصي
Special
پژوهشي
Research
<p><strong>Objective</strong>: The aim of this study was to evaluate the effect of zinc and magnesium supplementation on glycemic control and serum insulin in type 2 diabetic patients.</p>
<p><strong>Materials and Methods</strong>: In this randomized clinical trial 70 diabetic patients who referred to Yazd Diabetes Center were selected. Subjects received 500 mg/day magnesium oxide or 100 mg/day zinc sulfate randomly for 8 weeks. At the start and end of treatment period fasting blood sugar (FBS), 2 hour postprandial glucose (2-hpp), glycated hemoglobin (HbA1C) and fasting insulin level were measured.</p>
<p><strong>Results</strong>: Magnesium and Zinc supplementation for 8 weeks cause significantly decrease in HbA1c (<em>P</em>=0.005, <em>P</em>=0.001).No significantly difference was observed after trial between magnesium and zinc groups in FBS (42.08 ±7.43 vs. 35.15 ± 6.52) (<em>P</em>=0.97), HbA1C (1.22±0.21 vs. 1.77±0.32) (<em>P</em>=0.07) and fasting serum insulin (39.81 ±7.03 vs.36.68±6.81) (<em>P</em>=0.83) respectively.</p>
<p><strong>Conclusion</strong>: Results of this study showed that 500 mg/day magnesium oxide or 100 mg/day zinc sulfate administration for 8 weeks could improve HbA1C in type 2 diabetic patients and this effect is same in two groups. But more studies for evaluating effect of magnesium and zinc supplementation on type 2 diabetic patients were suggested.</p>
Diabetes type 2, Magnesium, Zinc, HbA1C.
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http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-30-114&slc_lang=en&sid=1
Arezoo
Afkhami-Ardekani