en تخصصي Special پژوهشي Research <strong>Objective:</strong> This study analyses the patients&#39; factors can influence the attitude to follow or not the therapeutic weight-loss plan after national lockdown measures adopted from March 2020 to May 2020.<br> <strong>Materials and Methods</strong><strong>:</strong> Patients that visited a private nutritional center in March 2020 were included in this retrospective observational study. All relevant characteristics were noted. In May 2020, patients who did not attend the follow-up visit <a name="_Hlk67746012">were labeled as &quot;abandoned&quot;. </a>Variation in Body Mass Index (BMI) was noted in the second visit. Univariate logistic regression was performed to test the influence on dependent variables (lost follow-up). Odds Ratio (OR) was calculated. According to BMI distribution, we performed a Student T-test (&alpha;= 0.05) or Wilcoxon test (&alpha;= 0.05) to test BMI variation in patients that attended the follow-up visit. A <em>P</em>-value< 0.05 was considered statistically significant.<br> <strong>Results:</strong> Our population consisted of 77 patients, and 26 patients (33.8%, CI_95% 23.4-45.4%) were labelled as &quot;abandoned&quot;. Age&ge; 54 years old (OR= 8.9048, CI_95%:1.888-41.9822, <em>P</em>-value= 0.0057) and suffering from hypertension (OR= 4.8706, CI_95%:1.4284-16.6076, <em>P-</em>value= 0.0114) were factors associated with the abandon follow-up visits. Wilcoxon test for BMI variation resulted statistically significant (May BMI 29.5 kg/m² vs March BMI 29.4 kg/m², <em>P-</em>value= 0.0094).<br> <strong>Conclusion</strong><strong>:</strong> Age and hypertension are related to the risk of abandoning healthcare services after ending the national lockdown. The losing follow-up phenomenon could worsen clinical conditions and reduce life expectancy. An increase in BMI during lockdown should be interpreted as a personal difficulty in complying with therapeutic prescriptions.<br> &nbsp; COVID-19, Pandemic, Lockdown, Obesity, Diet 117 124 http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-30-314&slc_lang=en&sid=1 Mariana Di Lorenzo 0000-0002-6895-6485 No Department of Biology, University of Naples Silvia Mascolo 0000-0003-1696-1474 Yes 2. Department of Infectious Diseases, AORN dei Colli, Cotugno Hospital, Napoli, Italy. Antonio Romanelli 0000-0003-2829-0436 No Department of Anaesthesia and Intensive Care, AOU San Giovanni di Dio e Ruggi D'Aragona, Salerno, Italy.