en تخصصي Special پژوهشي Research OBJECTIVE: For decades, exercise has been considered as a cornerstone for managing diabetes. The current study aimed to determine the effects of short-term exercise on blood glucose, lipids and HbA1C in type-2 diabetes mellitus. MATERIALS AND METHODS: A total of 61 diabetic patients were randomly selected. Later, subjects with capability of doing exercise took part in a special four-week exercise program. The blood glucose, lipid levels (before and after 4 weeks) and HbA1C (before and three months after exercise program) of 32 subjects were measured and compared in the time scales. RESULTS: Our results showed a significant reduction in blood glucose and lipid concentrations. However, the reduction observed in HbA1C was not significant (P=0.12). Comparison of pre- and post-exercise results demonstrated a significant improved glycemic control. CONCLUSION: The findings confirm the benefits of exercise training in type 2 diabetic patients. There are many studies which support the importance of physical activities program in controlling and preventing the common metabolic disorder and its complication Diabetes, Short-term exercise, Blood glucose level, HbA1C 19 25 http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-30-7&slc_lang=en&sid=1 Azam Ghorbani No 1. Metabolic Disease Research Center, Qazvin university Of Medical Sciences, Qazvin, Iran. Amir Ziaee Yes Metabolic Disease Research Center, Qazvin university Of Medical Sciences, Qazvin, Iran. Zohreh Yazdi No Metabolic Disease Research Center, Qazvin university Of Medical Sciences, Qazvin, Iran. Mohammad-Hosein Khoeyni No Qazvin University of Medical Sciences, Qazvin, Iran Mahsa Khoshpanjeh No Metabolic Disease Research Center, Qazvin university Of Medical Sciences, Qazvin, Iran.