Iranian Journal of Diabetes and Obesity
IJDO
Medical Sciences
http://ijdo.ssu.ac.ir
1
admin
2008-6792
2345-2250
8
7
14
8888
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en
jalali
1403
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gregorian
2024
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online
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fulltext
en
Prevalence and Impact of Thyroid Disorders on Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study
تخصصي
Special
پژوهشي
Research
<span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Objective</span></b><b><span new="" roman="" style="font-family:" times="">:</span></b> <span new="" roman="" style="font-family:" times="">Diabetes and thyroid disorders (TD) are two prevalent endocrine conditions in adults. While the association between TD and type 1 diabetes is well documented, the relationship between type 2 diabetes mellitus (T2DM) and TD remains unclear due to its complex mechanisms and the involvement of multiple variables. This study aimed to evaluate the prevalence of TD in patients with T2DM referred to Yazd Diabetes Research Center in 2019.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Materials and Methods</span></b><b><span dir="RTL" new="" roman="" style="font-family:" times="">:</span></b><b> </b><span new="" roman="" style="font-family:" times="">This cross-sectional descriptive study included 411 patients with T2DM. Data were collected using a checklist comprising demographic information (age, sex, type of drug used, duration of diabetes) and clinical and laboratory information. Data were analyzed using SPSS version 24 software.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span new="" roman="" style="font-family:" times="">Results</span></b><b><span dir="RTL" new="" roman="" style="font-family:" times="">:</span></b> <span new="" roman="" style="font-family:" times="">Among the 411 patients with T2DM, 352 (85.6%) had no TD, 38 (9.24%) had hypothyroidism, and 21 (5.10%) had hyperthyroidism. There were no significant differences among groups in terms of gender (<i>P</i>= 0.269), age (<i>P</i>= 0.154), fasting blood sugar (FBS) level (<i>P</i>= 0.196), type of treatment (<i>P</i>= 0.9), and duration of T2DM (<i>P</i>= 0.138). However, a significant relationship was found between TD and the average level of glycosylated hemoglobin (HbA1c) (<i>P</i>= 0.021).</span><span dir="RTL" lang="FA" style="font-size:10.5pt"><span style="line-height:115%"><span style="font-family:"Times New Roman","serif""></span></span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="text-justify:inter-ideograph"><span style="line-height:115%"><span calibri="" style="font-family:"><b><span lang="EN" style="font-size:10.5pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b> <span style="font-size:10.5pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">This study highlights a significant prevalence of TD among patients with T2DM, particularly noting the impact on HbA1c levels. Regular screening for TD in patients with T2DM is recommended to improve glycemic control and overall diabetes management. Further research is needed to elucidate the mechanisms linking TD and T2DM and to develop targeted interventions.</span></span></span></span></span></span></span><br>
Type 2 diabetics mellitus, Thyroid disorders, Glycated Hemoglobin A, Prevalence
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143
http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-30-416&slc_lang=en&sid=1
Mohammad Reza
Salimian