Iranian Journal of Diabetes and Obesity

en The Erythrocyte Sedimentation Rate in Type 1 Diabetes Mellitus تخصصي Special پژوهشي Research Objective: This study aimed to investigate the comparison of the Erythrocyte Sedimentation Rate (ESR) levels in patients with type 1 diabetes mellitus (T1DM) rather than the standard ESR rate as the reference. Materials and Methods: In this analytical cross-sectional study 80 individuals with T1DM under 14 years of age were selected from Diabetes Research Center from 2021-2022. Sampling was done by available methods. Demographic information such as age, gender, HbA1c, and ESR level was recorded. The collected data were entered into SPSS v.22 software. Pearson correlation was used for association and t-test was used for comparing means. A significance level of P < 0.05 was considered. Results: thirty three (41.2%) were male and 47 (58.8%) were female. The mean (±SD) age was 9.50 (± 0.414) years. The mean (±SD) ESR in the studied samples was 11.60(±6.475), which had a significant difference with the ESR value of 10 (P= 0.031). Moreover, the ESR of both groups of studied boys -and girls was significantly higher than the standard upper limit of the society (P= 0.0001). Additionally, ESR had a statistical relationship with HbA1c (P= 0.016) and no significant relationship with age (P= 0.730). Conclusion: ESR levels in children with T1D were significantly elevated, indicating systemic inflammation. ESR also showed a statistical relationship with HbA1c levels, suggesting its potential as a valuable marker for disease activity and management in T1D patients.   Type 1 diabetes, Erythrocyte sedimentation rate, Inflammation 186 190 http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-30-422&slc_lang=en&sid=1 Fariba Binesh No Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Sahar Paknejadi No Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Nasim Namiranian No Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Mahtab Ordooei 0000-0002-2466-9070 Yes Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.