Volume 11, Issue 3 (volume 11, number 3 2019)                   IJDO 2019, 11(3): 173-180 | Back to browse issues page


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Fakhri S, shakeryan S, Alizadeh A, Shahryari A. Effect of 6 Weeks of High Intensity Interval Training with Nano-curcumin Supplement on Antioxidant Defense and Lipid Peroxidation in Overweight Girls- Clinical Trial. IJDO. 2019; 11 (3) :173-180
URL: http://ijdo.ssu.ac.ir/article-1-511-en.html
Associate Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Abstract:   (821 Views)
Objective: Thepurpose of this study was to investigate the effect of 6 weeks of HIIT training combining nano-curcumin supplement on antioxidant defense and lipid degradation in overweight girls.
Materials and Methods: The research method was semi-experimental study. Accordingly, 48 overweight girl students were randomly divided into four groups: training (n=12), training-supplement (n=12), supplement (n=12) and control group (n=12). Supplement groups consumed 80 mg nano-curcumin capsule daily. Training groups performed an exercise protocol of HIIT training with maximum heart rate for 6 weeks (three sessions per week). The control group did not have any regular exercise. Blood samples were obtained before and after training period for antioxidant indicators and lipid degradation measurement. T-test and one-way analysis of variance were used for the evaluation of within-group and between-group differences, respectively. 
Results: A significant increase was observed in serum levels of Malondialdehyde (P-value= 0.004) in the training group after 6 weeks. Also, there was a significant increase in serum Glutathione (P-value= 0.001), Superoxide dismutase (P-value= 0.006) and Catalase indexes (P-value= 0.01) in the supplement group. Moreover, a significant increase in catalase (P-value= 0.001), glutathione (P-value= 0.006), superoxide dismutase (P-value= 0.015) and glutathione peroxidase indexes (P-value= 0.05) and a significant decrease in malondialdehyde (P-value= 0.009) were observed in the training supplement group.
Conclusion: A positive antioxidant effect was seen, so taking curcumin supplement along with exercises may have beneficial effects on reinforcement the antioxidant system and prevention of lipid peroxidation in overweight individuals.
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Type of Study: Research | Subject: Special
Received: 2020/02/15 | Accepted: 2020/02/15 | Published: 2020/02/15

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