Iranian Journal of Diabetes and Obesity
Shahid Sadoughi University Of Medical Sciences
Thu, Apr 25, 2024
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Volume 14, Issue 4 (volume 14, number 4 2022)
IJDO 2022, 14(4): 219-222 |
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Moradi S, Mohammadi S M, Namiranian N, Afkhami-Ardekani M, Afkhami-Ardakani O. The Effect of Oral Selenium on the Size of Thyroid Nodules in Patients with Benign Thyroid nodules: A Brief Study. IJDO 2022; 14 (4) :219-222
URL: http://ijdo.ssu.ac.ir/article-1-747-en.html
URL: http://ijdo.ssu.ac.ir/article-1-747-en.html
Samane Moradi 
, Seyed Mohammad Mohammadi , Nasim Namiranian , Mohammad Afkhami-Ardekani * , Omid Afkhami-Ardakani
, Seyed Mohammad Mohammadi , Nasim Namiranian , Mohammad Afkhami-Ardekani * , Omid Afkhami-Ardakani
Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract: (400 Views)
Objective: The thyroid gland is susceptible to the formation of nodules. Therefore, due to the critical role of selenium in the function of the thyroid gland, the impact of this element on the size and volume of this organ and its nodules were examined.
Materials and Methods: During three months, two groups consisting of 30 patients with benign thyroid nodules who were referred to Baghaeipour Endocrinology Clinic were given daily doses of 100 and 200 micrograms of selenium, and a control group of 30 people without selenium consumption were assessed.
Results: The results of intergroup analysis detected that the mean (±SD) of nodules length in the 100 µg selenium consumer group was 17.13 (±7.9) and 14.93 (±6.01) before and after intervention respectively (P= 0.008). About the nodules height in the 200 µg selenium consumer group, the mean (±SD) was 9.3 (±2.8) and 8.93 (±2.71) before and after intervention in that order (P= 0.001).
Conclusion: Our findings suggest that selenium has been effective in the size and volume of the
nodule and thyroid gland, as well as the TSH hormone, and further studies are needed to determine its therapeutic approach and efficacy.
Materials and Methods: During three months, two groups consisting of 30 patients with benign thyroid nodules who were referred to Baghaeipour Endocrinology Clinic were given daily doses of 100 and 200 micrograms of selenium, and a control group of 30 people without selenium consumption were assessed.
Results: The results of intergroup analysis detected that the mean (±SD) of nodules length in the 100 µg selenium consumer group was 17.13 (±7.9) and 14.93 (±6.01) before and after intervention respectively (P= 0.008). About the nodules height in the 200 µg selenium consumer group, the mean (±SD) was 9.3 (±2.8) and 8.93 (±2.71) before and after intervention in that order (P= 0.001).
Conclusion: Our findings suggest that selenium has been effective in the size and volume of the
nodule and thyroid gland, as well as the TSH hormone, and further studies are needed to determine its therapeutic approach and efficacy.
Type of Study: Research |
Subject:
Special
Received: 2022/06/24 | Accepted: 2022/10/5 | Published: 2022/11/19
Received: 2022/06/24 | Accepted: 2022/10/5 | Published: 2022/11/19
References
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2. Drutel A, Archambeaud F, Caron P. Selenium and the thyroid gland: more good news for clinicians. Clinical endocrinology. 2013;78(2):155-64. [DOI:10.1111/cen.12066]
3. Rasmussen LB, Schomburg L, Köhrle J, Pedersen IB, Hollenbach B, Hög A, et al. Selenium status, thyroid volume, and multiple nodule formation in an area with mild iodine deficiency. European Journal of Endocrinology. 2011;164(4):585-90. [DOI:10.1530/EJE-10-1026]
4. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26(1):1-33. [DOI:10.1089/thy.2015.0020]
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