Iranian Journal of Diabetes and Obesity
Shahid Sadoughi University Of Medical Sciences
Sun, Nov 24, 2024
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Volume 6, Issue 1 (3-2014)
IJDO 2014, 6(1): 23-27 |
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Mohammadabadi F, Vafaiyan Z, Hosseini S M, Aryaie M, Eshghinia S. Assessment of Insulin Resistance with Two Methods: HOMA-IR and TyG Index in Iranian Obese Women. IJDO 2014; 6 (1) :23-27
URL: http://ijdo.ssu.ac.ir/article-1-180-en.html
URL: http://ijdo.ssu.ac.ir/article-1-180-en.html
Fahimeh Mohammadabadi 
, Zahra Vafaiyan , Seyed Mehran Hosseini , Mohammad Aryaie , Samira Eshghinia *
, Zahra Vafaiyan , Seyed Mehran Hosseini , Mohammad Aryaie , Samira Eshghinia *
PhD of Nutrition; Metabolic Disorders Research Center, Departments of Biochemistry and Nutrition. Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Abstract: (5596 Views)
Objective: The aim of the present study is assessment of insulin resistance (IR) in obese women by TyG-Index and compared with the HOMA-IR index.
Materials and Methods: This cross-sectional study was performed on 61 obese women aged 18-45 years. Weights, height, waist circumference (WC) were measured and body mass index (BMI) was calculated and recorded. A sample of fasting serum was collected to determine the glucose, triglyceride, insulin, total cholesterol, HDL-C and LDL-C concentration. HOMA-IR and TyG-Index were calculated as markers of insulin resistance.
Results: The mean age of the precipitants was 32.5 ±0.79 years old and the mean weight was 86.0±1.7 Kg. The number of people with IR who determined by HOMA and TyG index were 21(34%) and 36(61%), respectively. There was a significant relationship between HOMA-IR and TyG Index, r= 0.044 (P<0.001).
Conclusion: TyG index represents a useful and accessible tool for assessment of IR instead HOMA_IR in Iranian population, but more researches with greater sample size and via gold standard lab test need to evaluate the specificity and sensitivity of this new method.
Type of Study: Research |
Subject:
Special
Received: 2014/12/22 | Accepted: 2014/12/22 | Published: 2014/12/22
Received: 2014/12/22 | Accepted: 2014/12/22 | Published: 2014/12/22
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