Volume 10, Issue 3 (volume 10, number 3 2018)                   IJDO 2018, 10(3): 151-158 | Back to browse issues page

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Roozbayani M. miR-29 as Indicator of Health and Disease in Sports Medicine - A Review . IJDO 2018; 10 (3) :151-158
URL: http://ijdo.ssu.ac.ir/article-1-431-en.html
Assistant Professor of Exercise Physiology, Department of Exercise Physiology, Boroujerd, Islamic Azad University, Boroujerd, Iran
Abstract:   (2280 Views)
Recent research is about the role of miR-29 accompanied by various conditions especially during the physical activity is a case of special attention, such as high intensity interval training (HIIT) and continuous aerobic training (CT) protective in heart, renal, lung, liver  and even immune system adaptation. Since recent studies indicated the rolls of miR family on health and disease such as the effect of miR on health parameters evaluation and cardiovascular-respiratory, diabetic cardiomyopathy, diabetes, hypertension, myocardial infarction, gastric and breast cancer. Blocking harmful genes such as COL-1, CTGF, SMAD3, TGF-β, NFK-B and genes expression related to health such as miR-29 is a primary approach in treatment of some diseases. Meanwhile sports as HIIT and CT can be safe approach for genes expression related health and blocking harmful genes. This regulations applies by miRs especially miR-29 that is one mystery regulator in variety of diseases. We will give a brief account of relation between sports activities and miR-29 expression in this review.

Full-Text [PDF 133 kb]   (879 Downloads)    
Type of Study: Review | Subject: Special
Received: 2018/12/16 | Accepted: 2018/12/16 | Published: 2018/12/16

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