Iranian Journal of Diabetes and Obesity
Shahid Sadoughi University Of Medical Sciences
Mon, May 6, 2024
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Volume 15, Issue 1 (volume 15, number 1 2023)
IJDO 2023, 15(1): 25-33 |
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Mirdehghan M, Injinari N, Vakili M, Namiranian N. Evaluation of Sexual Dysfunction and Related Factors in Iranian Men with Type 2 Diabetes: A Cross-Sectional Study. IJDO 2023; 15 (1) :25-33
URL: http://ijdo.ssu.ac.ir/article-1-775-en.html
URL: http://ijdo.ssu.ac.ir/article-1-775-en.html
Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Abstract: (341 Views)
Objective: Recently, the association between sexual dysfunction (SD) and diabetes has been proven in various studies. The study aimed to determine the frequency of SD and identify risk factors related to SD in men with Type 2 diabetes mellitus (T2DM).
Materials and Methods: The cross-sectional study was conducted on 114 men with T2DM who had referred to the Yazd Diabetes Center from 2019-2020. All of them filled out a standard questionnaire with a specified validity and reliability. The analysis was performed using ANOVA and Chi-square by SPSS, version 22 software.
Results: The mean age of participants was 52.48 (±5.33). The SD frequency was 73.7%. The mean SD score was 17.89 (±12). There was a significant relationship between the total SD and neuropathy (P: 0.0001), retinopathy (P: 0.0001), nephropathy (P: 0.023), type of treatment (P: 0.0001), age (P: 0.0001) and addiction (P: 0.031). There was no significant relationship between the total SD score and hyperlipidemia (P: 0.371), hypertension (P: 0.683), Hb1Ac (P: 0.816), duration of diabetes (P: 0.101) and smoking (P: 0.29).
Conclusion: Due to the high frequency of sexual dysfunction in men with T2DM, it is recommended that SD be considered as an important complication in these patients so that by identifying indicators related to this complication in patients with diabetes, sexual health clinics take the necessary measures to solve sexual problems in these patients.
Materials and Methods: The cross-sectional study was conducted on 114 men with T2DM who had referred to the Yazd Diabetes Center from 2019-2020. All of them filled out a standard questionnaire with a specified validity and reliability. The analysis was performed using ANOVA and Chi-square by SPSS, version 22 software.
Results: The mean age of participants was 52.48 (±5.33). The SD frequency was 73.7%. The mean SD score was 17.89 (±12). There was a significant relationship between the total SD and neuropathy (P: 0.0001), retinopathy (P: 0.0001), nephropathy (P: 0.023), type of treatment (P: 0.0001), age (P: 0.0001) and addiction (P: 0.031). There was no significant relationship between the total SD score and hyperlipidemia (P: 0.371), hypertension (P: 0.683), Hb1Ac (P: 0.816), duration of diabetes (P: 0.101) and smoking (P: 0.29).
Conclusion: Due to the high frequency of sexual dysfunction in men with T2DM, it is recommended that SD be considered as an important complication in these patients so that by identifying indicators related to this complication in patients with diabetes, sexual health clinics take the necessary measures to solve sexual problems in these patients.
Type of Study: Research |
Subject:
Special
Received: 2022/12/1 | Accepted: 2023/02/9 | Published: 2023/03/19
Received: 2022/12/1 | Accepted: 2023/02/9 | Published: 2023/03/19
References
1. Leeners B, Tschudin S, Wischmann T, Kalaitzopoulos DR. Sexual dysfunction and disorders as a consequence of infertility: a systematic review and meta-analysis. Human Reproduction Update. 2023;29(1):95-125. [DOI:10.1093/humupd/dmac030]
2. Chen L, Shi GR, Huang DD, Li Y, Ma CC, Shi M, et al. Male sexual dysfunction: A review of literature on its pathological mechanisms, potential risk factors, and herbal drug intervention. Biomedicine & Pharmacotherapy. 2019;112:108585. [DOI:10.1016/j.biopha.2019.01.046]
3. Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas. Diabetes research and clinical practice. 2019;157:107843. [DOI:10.1016/j.diabres.2019.107843]
4. Esteghamati A, Larijani B, Aghajani MH, Ghaemi F, Kermanchi J, Shahrami A, Saadat M, Esfahani EN, Ganji M, Noshad S, Khajeh E. Diabetes in Iran: prospective analysis from first nationwide diabetes report of National Program for Prevention and Control of Diabetes (NPPCD-2016). Scientific reports. 2017;7(1):1-0. [DOI:10.1038/s41598-017-13379-z]
5. Mirzaei M, Rahmaninan M, Mirzaei M, Nadjarzadeh A, Dehghani Tafti AA. Epidemiology of diabetes mellitus, pre-diabetes, undiagnosed and uncontrolled diabetes in Central Iran: results from Yazd health study. BMC public health. 2020;20:1-9. [DOI:10.1186/s12889-020-8267-y]
6. Farhadi Z, Khaksari M. A Review on 17-β estradiol a Potent Therapeutic Factor of Diabetic Cardiomyopathy. Iranian Journal of Diabetes and Obesity. 2022 ;14(3):183-8. [DOI:10.18502/ijdo.v14i3.10745]
7. Pearce I, Simó R, Lövestam‐Adrian M, Wong DT, Evans M. Association between diabetic eye disease and other complications of diabetes: implications for care. A systematic review. Diabetes, obesity and metabolism. 2019;21(3):467-78. [DOI:10.1111/dom.13550]
8. Bekele BB. The prevalence of macro and microvascular complications of DM among patients in Ethiopia 1990-2017: Systematic review. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2019;13(1):672-7. [DOI:10.1016/j.dsx.2018.11.046]
9. Aboutorabi-Zarchi M, Jam Ashkezari S, Gholami S, Razavi-Ratki SK, Namiranian N. Is Knowledge of type 2 diabetic patients about stroke acceptable-a cross sectional study. Iranian Journal of Diabetes and Obesity. 2019;11(1):22-7.
10. Isidro ML. Sexual dysfunction in men with type 2 diabetes. Postgraduate medical journal. 2012;88(1037):152-9. [DOI:10.1136/postgradmedj-2011-130069]
11. Sharma JK, Rohatgi A, Sharma D. Diabetic autonomic neuropathy: a clinical update. Journal of the Royal College of Physicians of Edinburgh. 2020;50(3):269-73. [DOI:10.4997/jrcpe.2020.310]
12. Gandhi J, Dagur G, Warren K. Effect of diabetes mellitus on sexual arousal and intercourse. Transl Biomed. 2016;7(2):2-5. [DOI:10.21767/2172-0479.100057]
13. Firouzkouhi M, Abdollahimohammad A. Lived Experiences of Type 2 Diabetes with Irreversible Complications: A Qualitative Research. Iranian Journal of Diabetes and Obesity. 2022;14(3):176-82. [DOI:10.18502/ijdo.v14i3.10744]
14. Bąk E, Marcisz C, Krzemińska S, Dobrzyn-Matusiak D, Foltyn A, Drosdzol-Cop A. Relationships of sexual dysfunction with depression and acceptance of illness in women and men with type 2 diabetes mellitus. International journal of environmental research and public health. 2017;14(9):1073. [DOI:10.3390/ijerph14091073]
15. Asefa A, Nigussie T, Henok A, Mamo Y. Prevalence of sexual dysfunction and related factors among diabetes mellitus patients in Southwest Ethiopia. BMC endocrine disorders. 2019;19(1):1-8. [DOI:10.1186/s12902-019-0473-1]
16. Boeri L, Capogrosso P, Ventimiglia E, Schifano N, Montanari E, Montorsi F, et al. Sexual dysfunction in men with prediabetes. Sexual medicine reviews. 2020 ;8(4):622-34. [DOI:10.1016/j.sxmr.2018.11.008]
17. Garza-Gangemi AM, Sotomayor-de Zavaleta M. Erectile dysfunction therapy in countries where implant is economically not feasible. Translational Andrology and Urology. 2017;6(2):176. [DOI:10.21037/tau.2017.04.15]
18. Rahimi M, Reshadat S, Farid Marandi B, Zakiei A. Factors associated with sexual function and sexual satisfaction in male patients with diabetes type 2. Journal of Mazandaran University of Medical Sciences. 2018;28(164):164-9. (in Persian)
19. Lombard A, Duffau H. Sexual dysfunction of patients with diffuse low-grade glioma: a qualitative review of a neglected concern. Cancers. 2022;14(12):3025. [DOI:10.3390/cancers14123025]
20. Alikamali M, Khodabandeh S, Motesaddi M. Sexual dysfunction in males and females with type 2 diabetes referring to healthcare centers of Zarand, Kerman: a cross-sectional study. Shiraz E-Medical Journal. 2019;20(8). [DOI:10.5812/semj.84268]
21. Chandrashekar V, Steger RW, Bartke A, Fadden CT, Kienast SG. Influence of diabetes on the gonadotropin response to the negative feedback effect of testosterone and hypothalamic neurotransmitter turnover in adult male rats. Neuroendocrinology. 1991;54(1):30-5. [DOI:10.1159/000125847]
22. Fallahi M, Mozaffari-Khosravi H, Afkhami-Ardekani M, Dehghani A. Evaluation of sexual function in men with diabetes mellitus type 2-Yazd Diabetes Research Center. Iranian Journal of Diabetes and Obesity. 2014;6(3):136-41.
23. Bahar A, Elyasi F, Moosazadeh M, Afradi G, Kashi Z. Sexual dysfunction in men with type II diabetes. Caspian Journal of Internal Medicine. 2020;11(3):295.
24. Selvin E, Burnett AL, Platz EA. Prevalence and risk factors for erectile dysfunction in the US. The American journal of medicine. 2007;120(2):151-7. [DOI:10.1016/j.amjmed.2006.06.010]
25. Rizk PJ, Kohn TP, Pastuszak AW, Khera M. Testosterone therapy improves erectile function and libido in hypogonadal men. Current opinion in urology. 2017;27(6):511. [DOI:10.1097/MOU.0000000000000442]
26. Corona G, Mannucci E, Petrone L, Ricca V, Balercia G, Mansani R, et al. Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic. International journal of impotence research. 2006;18(2):190-7. [DOI:10.1038/sj.ijir.3901391]
27. Corona G, Giorda CB, Cucinotta D, Guida P, Nada E, Subito-De Study Group. Sexual dysfunction in type 2 diabetes at diagnosis: progression over time and drug and non-drug correlated factors. PloS one. 2016;11(10):e0157915. [DOI:10.1371/journal.pone.0157915]
28. Camacho ME, Reyes-Ortiz CA. Sexual dysfunction in the elderly: age or disease?. International journal of impotence research. 2005;17(1):S52-6. [DOI:10.1038/sj.ijir.3901429]
29. Sahin MO, Sen V, Gunduz G, Ucer O. Effect of smoking cessation on sexual functions in men aged 30 to 60 years. International braz j urol. 2020;46:642-8. [DOI:10.1590/s1677-5538.ibju.2019.0541]
30. Maiorino MI, Bellastella G, Esposito K. Diabetes and sexual dysfunction: current perspectives. Diabetes, metabolic syndrome and obesity: targets and therapy. 2014;7:95. [DOI:10.2147/DMSO.S36455]
31. Biebel MG, Burnett AL, Sadeghi-Nejad H. Male sexual function and smoking. Sexual medicine reviews. 2016;4(4):366-75. [DOI:10.1016/j.sxmr.2016.05.001]
32. Heikkilä A, Kaipia A, Venermo M, Kautiainen H, Korhonen P. Relationship of blood pressure and erectile dysfunction in men without previously diagnosed hypertension. The Journal of Sexual Medicine. 2017;14(11):1336-41. [DOI:10.1016/j.jsxm.2017.09.007]
33. Foy CG, Newman JC, Berlowitz DR, Russell LP, Kimmel PL, Wadley VG, et al. Blood pressure, sexual activity, and erectile function in hypertensive men: baseline findings from the Systolic Blood Pressure Intervention Trial (SPRINT). The journal of sexual medicine. 2019;16(2):235-47. [DOI:10.1016/j.jsxm.2018.12.007]
34. Sharifi F, Asghari M, Jaberi Y, Salehi O, Mirzamohammadi F. Independent predictors of erectile dysfunction in type 2 Diabetes mellitus: Is it true what they say about risk factors?. International Scholarly Research Notices. 2012;2012:1-5. [DOI:10.5402/2012/502353]
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