Relationship between Probiotics and Type 2 Diabetes Mellitus: A Review

Kheirkhah, Amir Hossein; Forouzani-Moghaddam, Mohammad Javad; Afkhami-Ardekani, Mohammad

doi:10.18502/ijdo.v15i2.12971

Volume 15, Issue 2 (6-2023) IJDO 2023, 15(2): 119-128 | Back to browse issues page

‎ 10.18502/ijdo.v15i2.12971

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Kheirkhah A H, Forouzani-Moghaddam M J, Afkhami-Ardekani M. Relationship between Probiotics and Type 2 Diabetes Mellitus: A Review. IJDO 2023; 15 (2) :119-128
URL: http://ijdo.ssu.ac.ir/article-1-795-en.html

Relationship between Probiotics and Type 2 Diabetes Mellitus: A Review

Amir Hossein Kheirkhah

, Mohammad Javad Forouzani-Moghaddam

, Mohammad Afkhami-Ardekani ^*

Professor of Endocrinology, Diabetes Research Center, Shahid Sadougdi University of Medical Sciences, Yazd, Iran.

Abstract: (474 Views)

Objective: Diabetes is a chronic medical condition that can be caused by either inherited or acquired insufficiency insulin secretion, or the body's inability to effectively utilize the insulin it produces. There are three primary classifications of diabetes: type 1, type 2, and gestational diabetes. Type 2 diabetes mellitus (T2DM) is characterized by elevated levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c), indicating a disturbance in glucose metabolism. The term "probiotics" refers to living microorganisms that provide beneficial effects on the host's health. The effects of probiotics on T2DM in humans have shown conflicting results. Some studies have demonstrated that probiotic treatment substantially reduces HbA1c, FBG, or insulin resistance (IR) in patients with T2DM. However, other studies have found no significant difference between probiotic-treated patients and those receiving a placebo.. The use of probiotics was found to enhance glucose metabolism and HbA1c levels in individuals with T2DM. These findings are in line with previous reviews conducted on this topic.

Keywords: Diabetes, Probiotics, Insulin

Full-Text [PDF 465 kb] (267 Downloads)

Type of Study: Research | Subject: Special
Received: 2023/02/9 | Accepted: 2023/05/8 | Published: 2023/06/20

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