Effect of Interval Resistance Training with Different Intensities on Some Selected Adipokines in Obese Men

Yazdkhasti, Ensieh; Seifi Skishahr, Farnaz; Farzizadeh, Reza

doi:10.18502/ijdo.v15i4.14554

Volume 15, Issue 4 (volume 15, number 4 2023) IJDO 2023, 15(4): 208-217 | Back to browse issues page

‎ 10.18502/ijdo.v15i4.14554

Mendeley

Zotero

RefWorks

Yazdkhasti E, Seifi Skishahr F, Farzizadeh R. Effect of Interval Resistance Training with Different Intensities on Some Selected Adipokines in Obese Men. IJDO 2023; 15 (4) :208-217
URL: http://ijdo.ssu.ac.ir/article-1-832-en.html

Effect of Interval Resistance Training with Different Intensities on Some Selected Adipokines in Obese Men

Ensieh Yazdkhasti

, Farnaz Seifi Skishahr ^*

, Reza Farzizadeh

Associate Professor Department of Physical Education and Sport Science, Faculty of Educational Sciences and Psychology, University of Mohagheghe Ardabili, Ardabil, Iran.

Abstract: (145 Views)

Objective: Adipose tissue-derived adipokines affect cardiometabolic health. This study aimed to evaluate the effect of interval resistance training with different intensities on leptin, adiponectin, and acrosin levels in obese males.
Materials and Methods: Fourty-four obese males (27.70± 3.02 years) were randomly allocated into four groups: high intensity (HI), moderate intensity (MI), low intensity (LI), and control (C). Subjects of the HI, MI, and LI groups implemented the training program for 12 weeks, three sessions a week with intensities corresponding 80% 1RM, 60% 1RM, and 40% 1RM,, respectively. Body composition and plasma levels of leptin, adiponectin, and asprosin were evaluated before and after interval resistance training at different intensities.
Results: Following exercise, serum levels of leptin and asporin were significantly reduced in all groups (P< 0.01). The greatest reduction of leptin and asporin levels was recorded in the HI group (P= 0.001, P= 0.01) for leptin and asporsin levels, respectively. The level of adiponectin significantly decreased after exercise in all groups (P< 0.001, F= 12.44). The greatest reduction was observed in the HI group compared with the MI and UI group (P= 0.001).
Conclusion: Interval resistance training with different intensities can cause significant changes in leptin, asprosin, and adiponectin levels in obese men, and this improvement was better at high intensities.

Keywords: Obesity, Leptin, Adiponectin, Asprosin, Interval resistance training

Full-Text [PDF 513 kb] (83 Downloads)

Type of Study: Research | Subject: Special
Received: 2023/07/25 | Accepted: 2023/10/12 | Published: 2023/12/19

References

1. Ahmadi M, Abbassi Daloii A, Shadmehri S, Agghaei Bahmanbeglu N. Compare the effect of eight weeks aerobic and resistance training on Oxidant, antioxidant status and lipid profile in obese girls. Journal of Sport and Exercise Physiology. 2019;11(1):139-52.(in Persian)

2. Ouerghi N, Fradj MK, Duclos M, Bouassida A, Feki M, Weiss K, et al. Effects of high-intensity interval training on selected adipokines and cardiometabolic risk markers in normal-weight and overweight/obese young males-a pre-post test trial. Biology (Basel). 2022; 11 (6): 853. [DOI:10.3390/biology11060853]

3. Murawska-Ciałowicz E. Adipose tissue-morphological and biochemical characteristic of different depots. Advances in Hygiene and Experimental Medicine. 2017;71:466-84. [DOI:10.5604/01.3001.0010.3829]

4. Esler M, Straznicky N, Eikelis N, Masuo K, Lambert G, Lambert E. Mechanisms of sympathetic activation in obesity-related hypertension. Hypertension. 2006;48(5):787-96. [DOI:10.1161/01.HYP.0000242642.42177.49]

5. Ouerghi N, Fradj MK, Talbi E, Bezrati I, Feki M, Bouassida A. Association of selected adipokines with metabolic syndrome and cardio-metabolic risk factors in young males. Cytokine. 2020;133:155170. [DOI:10.1016/j.cyto.2020.155170]

6. Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. The Journal of clinical investigation. 2006;116(7):1784-92. [DOI:10.1172/JCI29126]

7. de Winter CD, Bastiaanse LP, Hilgenkamp TI, Evenhuis HM, Echteld MA. Overweight and obesity in older people with intellectual disability. Research in developmental disabilities. 2012;33(2):398-405. [DOI:10.1016/j.ridd.2011.09.022]

8. Azali Alamdari K, Khalafi M. The Effect of Aerobic Exercise on Serum Levels of Adiponectin and CRP and Insulin Resistance in Women with Metabolic Syndrome. Sport Physiology & Management Investigations. 2019;11(4):53-63.(in Persian)

9. Esteghamati A, Khalilzadeh O, Anvari M, Rashidi A, Mokhtari M, Nakhjavani M. Association of serum leptin levels with homeostasis model assessment-estimated insulin resistance and metabolic syndrome: the key role of central obesity. Metabolic syndrome and related disorders. 2009;7(5):447-52.(in Persian) [DOI:10.1089/met.2008.0100]

10. Ahima RS. Revisiting leptin's role in obesity and weight loss. The Journal of clinical investigation. 2008;118(7):2380-3. [DOI:10.1172/JCI36284]

11. Lee KW, Shin D. Prospective associations of serum adiponectin, leptin, and leptin-adiponectin ratio with incidence of metabolic syndrome: the Korean Genome and Epidemiology Study. International Journal of Environmental Research and Public Health. 2020;17(9):3287. [DOI:10.3390/ijerph17093287]

12. Lee SW, Rho JH, Lee SY, Kim JH, Cheong JH, Kim HY, et al. Leptin protects rat articular chondrocytes from cytotoxicity induced by TNF-α in the presence of cyclohexamide. Osteoarthritis and Cartilage. 2015;23(12):2269-78. [DOI:10.1016/j.joca.2015.06.005]

13. Romere C, Duerrschmid C, Bournat J, Constable P, Jain M, Xia F, et al. Asprosin, a fasting-induced glucogenic protein hormone. Cell. 2016;165(3):566-79. [DOI:10.1016/j.cell.2016.02.063]

14. Kajimura S. Advances in the understanding of adipose tissue biology. Nature reviews endocrinology. 2017;13(2):69-70. [DOI:10.1038/nrendo.2016.211]

15. Hayashino Y, Jackson JL, Hirata T, Fukumori N, Nakamura F, Fukuhara S, et al. Effects of exercise on C-reactive protein, inflammatory cytokine and adipokine in patients with type 2 diabetes: a meta-analysis of randomized controlled trials. Metabolism. 2014;63(3):431-40. [DOI:10.1016/j.metabol.2013.08.018]

16. Sepehrirad M, Valipour Dehnou V, Fathi MO. Effects of hict on serum lipids and glucose levels in elderly women. Iran Journal of Nursing. 2018;31(115):20-8.(in Persian) [DOI:10.29252/ijn.31.115.20]

17. Ara I, Perez-Gomez J, Vicente-Rodríguez G, Chavarren J, Dorado C, Calbet JA. Serum free testosterone, leptin and soluble leptin receptor changes in a 6-week strength-training programme. British journal of nutrition. 2006;96(6):1053-9. [DOI:10.1017/BJN20061956]

18. Ahmadizad S, Haghighi AH, Hamedinia MR. Effects of resistance versus endurance training on serum adiponectin and insulin resistance index. European journal of Endocrinology. 2007;157(5):625-31. [DOI:10.1530/EJE-07-0223]

19. Ghaderi M, Azizbeigi K. Hormonal responses to acute resistance exercise after branched-chain amino acids supplementation. International Medical Journal. 2014;22(1):1-5.

20. Akbarpour M. The effect of aerobic training on serum adiponectin and leptin levels and inflammatory markers of coronary heart disease in obese men. Biology of sport. 2013;30(1):21-7. [DOI:10.5604/20831862.1029817]

21. Bouassida A, Lakhdar N, Benaissa N, Mejri S, Zaouali M, Zbidi A, et al. Adiponectin responses to acute moderate and heavy exercises in overweight middle aged subjects. The Journal of sports medicine and physical fitness. 2010;50(3):330-5.

22. Ko JR, Seo DY, Kim TN, Park SH, Kwak HB, Ko KS, et al. Aerobic exercise training decreases hepatic asprosin in diabetic rats. Journal of clinical medicine. 2019;8(5):666-73. [DOI:10.3390/jcm8050666]

23. Wiecek M, Szymura J, Maciejczyk M, Kantorowicz M, Szygula Z. Acute anaerobic exercise affects the secretion of asprosin, irisin, and other cytokines-a comparison between sexes. Frontiers in physiology. 2018;9:1782. [DOI:10.3389/fphys.2018.01782]

24. Hazley L, Ingle LE, Tsakirides C, Carroll S, Nagi D. Impact of a short-term, moderate intensity, lower volume circuit resistance training programme on metabolic risk factors in overweight/obese type 2 diabetics. Research in Sports Medicine. 2010;18(4):251-62. [DOI:10.1080/15438627.2010.510049]

25. Ablove T, Binkley N, Leadley S, Shelton J, Ablove R. Body mass index continues to accurately predict percent body fat as women age despite changes in muscle mass and height. Menopause. 2015;22(7):727-30. [DOI:10.1097/GME.0000000000000382]

26. Qorbani Ganjeh Z, Gholami M, Nikbakht H. Effect of resistance training with different intensities on adiponectin and lipid profiles in overweight women. The Scientific Journal of Rehabilitation Medicine. 2019;8(4):47-55.(in Persian)

27. Baechle TR, Earle RW, editors. Essentials of strength training and conditioning. Human kinetics; 2008.

28. Burr JF, Rowan CP, Jamnik VK, Riddell MC. The role of physical activity in type 2 diabetes prevention: physiological and practical perspectives. The Physician and sportsmedicine. 2010;38(1):72-82. [DOI:10.3810/psm.2010.04.1764]

29. Jürimäe J, Jürimäe T. Leptin responses to short term exercise in college level male rowers. British Journal of Sports Medicine. 2005;39(1):6-9. [DOI:10.1136/bjsm.2003.008516]

30. Prestes J, Shiguemoto G, Botero JP, Frollini A, Dias R, Leite R,et al. Effects of resistance training on resistin, leptin, cytokines, and muscle force in elderly post-menopausal women. Journal of sports sciences. 2009;27(14):1607-15. [DOI:10.1080/02640410903352923]

31. Haghighi A, Hamedinia M. The effect of resistance training on serum leptin in obese men. Research Sport Science. 2008;20:13-25.(in Persian)

32. Fatouros IG, Tournis S, Leontsini D, Jamurtas AZ, Sxina M, Thomakos P, e. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. The Journal of Clinical Endocrinology & Metabolism. 2005;90(11):5970-7. [DOI:10.1210/jc.2005-0261]

33. Monikh K, Kashef M, Azad A, Ghasemnian A. Effects of 6 weeks resistance training on Body Composition, serum Leptin and muscle strength in non-athletic men. Internal Medicine Today. 2015;21(2):135-40.(in Persian) [DOI:10.18869/acadpub.hms.21.2.135]

34. Hamedinia M, Haghighi A. Investigation of effect of one session moderate and heavy resistance exercise on acute and delayed responses of leptin, insulin, cortisol, testosterone and 24-hour energy expenditure in healthy men. Iranian Journal of Endocrinology and Metabolism. 2011;13(1):67-73.(in Persian)

35. Saremi A, Shavandi N, Bayat N. The effect of aerobic training on ghrelin and leptin serum levels and sleep quality in obese and overweight men. Journal of Arak University of Medical Sciences. 2012;15(1):52-60.(in Persian)

36. Asad MR, Ferdosi MH, Yoosefi Z. The effects of three training methods endurance, resistance and concurrent on adiponectin resting levels in overweighed untrained men. Procedia-Social and Behavioral Sciences. 2012;46:440-4.(in Persian) [DOI:10.1016/j.sbspro.2012.05.138]

37. Haghighi AH, Yarahmadi H, IldarAbadi A. The effect of green tea and aerobic exercise on serum adiponectin and ghrelin. medical journal of mashhad university of medical sciences. 2015;57(8):904-12.(in Persian)

38. Klimcakova E, Polak J, Moro C, Hejnova J, Majercik M, Viguerie N, et al. Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men. The Journal of Clinical Endocrinology & Metabolism. 2006;91(12):5107-12. [DOI:10.1210/jc.2006-0382]

39. Mager U, Kolehmainen M, de Mello VD, Schwab U, Laaksonen DE, Rauramaa R, et al. Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome. European journal of endocrinology. 2008;158(4):499-510. [DOI:10.1530/EJE-07-0862]

40. Zhaosheng T, Li Y, Chengying G, Yun L, Lian Z. Effect of exercise on the expression of adiponectin mRNA and GLUT4 mRNA in type 2 diabetic rats. Journal of Huazhong University of Science and Technology [Medical Sciences]. 2005;25:191-3. [DOI:10.1007/BF02873574]

41. Wang CY, Lin TA, Liu KH, Liao CH, Liu YY, Wu VC, et al. Serum asprosin levels and bariatric surgery outcomes in obese adults. International journal of obesity. 2019;43(5):1019-25. [DOI:10.1038/s41366-018-0248-1]

42. Duerrschmid C, He Y, Wang C, Li C, Bournat JC, Romere C, et al. Asprosin is a centrally acting orexigenic hormone. Nature medicine. 2017;23(12):1444-53. [DOI:10.1038/nm.4432]

43. Schumann U, Qiu S, Enders K, Bosnyák E, Laszlo R, Machus K, et al. Asprosin, A Newly Identified Fasting-Induced Hormone Is Not Elevated In Obesity And Is Insensitive To Acute Exercise: 3592 Board# 39 June 3 8: 00 AM-9: 30 AM. Medicine & science in sports & exercise. 2017;49(5S):1023:23-30. [DOI:10.1249/01.mss.0000519807.24061.ca]

44. Sohn JW. Network of hypothalamic neurons that control appetite. BMB reports. 2015;48(4):229. [DOI:10.5483/BMBRep.2015.48.4.272]

45. Rezaeinezhad N, Ghanbari-Niaki A, Alizadeh R. The effect of circuit resistance training with different intensities on the agouti-related protein, insulin and glucose plasma levels in young men.Feyz Medical Science Journal. 2018;22(5):478-86.(in Persian)