Volume 17, Issue 3 (7-2025)                   IJDO 2025, 17(3): 198-205 | Back to browse issues page


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Afshar Naseri M B. Resistance Training as a Therapeutic Strategy for Managing Metabolic Syndrome in Women: A Comprehensive Review. IJDO 2025; 17 (3) :198-205
URL: http://ijdo.ssu.ac.ir/article-1-969-en.html
Master of Sport Applied Physiology, Exercise Physiology Department, Islamic Azad University Tehran North Branch. Tehran. Iran.
Abstract:   (20 Views)
This review investigates the vital role of resistance training as a therapeutic method for women with metabolic syndrome, a condition characterized by insulin resistance, high blood pressure, abnormal lipid levels, and central obesity. The primary goal of the review is to consolidate existing research on how resistance training impacts metabolic health in this group. A thorough review of peer-reviewed studies was conducted, especially those published in the last twenty years. The analysis focused on studies exploring how resistance training influences metabolic factors such as insulin sensitivity, glucose metabolism, lipid profiles, and body composition in women with metabolic syndrome. The literature indicates that resistance training significantly increases muscle mass, improves blood sugar regulation, and positively affects lipid profiles, reducing waist size, total cholesterol, and LDL cholesterol levels. Furthermore, the review emphasizes that resistance training enhances insulin sensitivity and decreases serum triglyceride levels. The review concludes that resistance training is crucial for managing metabolic syndrome in women, helping to improve metabolic health and overall well-being.
 
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Type of Study: Research | Subject: Special
Received: 2024/08/25 | Accepted: 2025/06/10 | Published: 2025/07/28

References
1. Ghanbari-Niaki A, Saeidi A, Gharahcholo L, Moradi-Dehbaghi K, Zare-Kookandeh N, Ahmadian M, et al. Influence of resistance training and herbal supplementation on plasma apelin and metabolic syndrome risk factors in postmenopausal women. Science & sports. 2020;35(2):109.e1-109.e5. [DOI:10.1016/j.scispo.2019.04.010]
2. Katz A. Brief periods of resistance training enhance insulin sensitivity in humans. Experimental Physiology. 2019; 104(4):458-59. [DOI:10.1113/EP087607]
3. Ahmad A, Soliman AA, Shaheen E, Obaya H. Effect of adding high-intensity interval training to diet and carboxytherapy on metabolic cardiovascular risk factors in women with metabolic syndrome. Gastroenterology Review/Przegląd Gastroenterologiczny. 2022;17(4):280-7. [DOI:10.5114/pg.2022.121822]
4. Komorian A, Kottenstette S, Magallanes E, Smith J, Burton CA. Does resistance training in patients with metabolic syndrome reduce cardiovascular risk factors?. Evidence-Based Practice. 2023;26(6):17-8. [DOI:10.1097/EBP.0000000000001698]
5. Tomeleri CM, Souza MF, Burini RC, Cavaglieri CR, Ribeiro AS, Antunes M, et al. Resistance training reduces metabolic syndrome and inflammatory markers in older women: A randomized controlled trial. Journal of Diabetes. 2018; 10(4):328-37. [DOI:10.1111/1753-0407.12614]
6. Andrade DC, Flores-Opazo M, Peñailillo L, Delgado-Floody P, Cano-Montoya J, Vásquez-Gómez JA, et al. Similar adaptations to 10 weeks concurrent training on metabolic markers and physical performance in young, adult, and older adult women. Journal of Clinical Medicine. 2021;10(23):5582. [DOI:10.3390/jcm10235582]
7. Hassan P, Maryam E. Comparison of two different resistance training intensities on metabolic syndrome risk factors in obese women. International Journal of Applied Exercise Physiology. 2019;8(1):74-83.
8. Sarin HV, Ahtiainen JP, Hulmi JJ, Ihalainen JK, Walker S, Küüsmaa-Schildt M, et al. Resistance training induces antiatherogenic effects on metabolomic pathways. Medicine & Science in Sports & Exercise. 2019;51(9):1866-75. [DOI:10.1249/MSS.0000000000002003]
9. Winnick JJ, Gaillard T, Schuster DP. Resistance training differentially affects weight loss and glucose metabolism of White and African American patients with type 2 diabetes mellitus. Ethnicity & disease. 2008;18(2):152-6.
10. Zupkauskiene J, Lauceviciene I, Ryliskyte L, Navickas P, Kizlaitis R, Laucevicius A. Ambulatory and successive home-based heart rate targeted aerobic training improves arterial parameters: a follow-up study in people with metabolic syndrome. Annals of Medicine. 2023;55(2):2250363. [DOI:10.1080/07853890.2023.2250363]
11. Consitt LA, Dudley C, Saxena G. Impact of endurance and resistance training on skeletal muscle glucose metabolism in older adults. Nutrients. 2019;11(11):2636. [DOI:10.3390/nu11112636]
12. Bucci M, Huovinen V, Guzzardi MA, Koskinen S, Raiko JR, Lipponen H, et al. Resistance training improves skeletal muscle insulin sensitivity in elderly offspring of overweight and obese mothers. Diabetologia. 2016;59:77-86. [DOI:10.1007/s00125-015-3780-8]
13. Ratajczak M, Krzywicka M, Szulińska M, Musiałowska D, Kusy K, Karolkiewicz J. Effects of 12-week combined strength and endurance circuit training program on insulin sensitivity and retinol-binding protein 4 in women with insulin-resistance and overweight or mild obesity: a randomized controlled trial. Diabetes, Metabolic Syndrome and Obesity. 2024:93-106. [DOI:10.2147/DMSO.S432954]
14. Nazari M, Gholamrezaei S, Shabani R. Effect of a Period Circuit Resistance Training on Components of the Metabolic Syndrome in Females with Type II Diabetes. Iranian Journal of Endocrinology and Metabolism 2016; 17(5) :362-370.(in Persian)
15. Evans PL, McMillin SL, Weyrauch LA, Witczak CA. Regulation of skeletal muscle glucose transport and glucose metabolism by exercise training. Nutrients. 2019;11(10):2432. [DOI:10.3390/nu11102432]
16. Pataky MW, Young WF, Nair KS. Hormonal and Metabolic Changes of Aging and the Influence of Lifestyle Modifications. Mayo Clinic Proceedings.Elsevier. 2021; 96(3):788-814. [DOI:10.1016/j.mayocp.2020.07.033]
17. Carr MC. The emergence of the metabolic syndrome with menopause. The Journal of Clinical Endocrinology & Metabolism. 2003;88(6):2404-11. [DOI:10.1210/jc.2003-030242]
18. Ziaei S, Mohseni H. Correlation between Hormonal Statuses and Metabolic Syndrome in Postmenopausal Women. Journal of Family Reproductive Health. 2013; 7(2):63-6.
19. Jorge ML, de Oliveira VN, Resende NM, Paraiso LF, Calixto A, Diniz AL, et al. The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 diabetes mellitus. Metabolism. 2011;60(9):1244-52. [DOI:10.1016/j.metabol.2011.01.006]
20. Westerman R, Kuhnt AK. Metabolic risk factors and fertility disorders: A narrative review of the female perspective. Reproductive Biomedicine & Society Online. 2022;14:66-74. [DOI:10.1016/j.rbms.2021.09.002]
21. Kianpour M, Mohammadi MF, Kazami A, Mokhtari F, Arti S, Ahmadi SM. Metabolic Syndrome and Assisted Reproductive Techniques. Journal of Family & Reproductive Health. 2023;17(2):80-85. [DOI:10.18502/jfrh.v17i2.12870]
22. Portha B, Grandjean V, Movassat J. Mother or father: who is in the front line? Mechanisms underlying the non-genomic transmission of obesity/diabetes via the maternal or the paternal line. Nutrients. 2019;11(2):233. [DOI:10.3390/nu11020233]
23. Sammut MJ, McBey DP, Sayal AP, Melling CJ. The effects of resistance exercise training on skeletal muscle metabolism and insulin resistance development in female rodents with type 1 diabetes. Journal of Diabetes Research. 2024;2024(1):5549762. [DOI:10.1155/2024/5549762]
24. Rodriguez-Hernandez M, Peart A, Suire K, Winkler D, Jones C, Wadsworth DD. The Effect Of Sit And Resistance Training On Metabolic Syndrome Outcomes For Black And White Women: 915. Medicine & Science in Sports & Exercise. 2022;54(9S):223. [DOI:10.1249/01.mss.0000877812.47414.01]
25. Turri-Silva N, Garner DM, Moosavi SH, Ricci-Vitor AL, Christofaro DG, Netto J, et al. Effects of resistance training protocols on nonlinear analysis of heart rate variability in metabolic syndrome. Brazilian Journal of Medical and Biological Research. 2018;51(8):e7459. [DOI:10.1590/1414-431x20187459]
26. Skidmore BL, Jones MT, Blegen M, Matthews TD. Acute effects of three different circuit weight training protocols on blood lactate, heart rate, and rating of perceived exertion in recreationally active women. Journal of sports science & medicine. 2012;11(4):660.
27. Mezghani N, Ammar A, Boukhris O, Abid R, Hadadi A, Alzahrani TM, et al. The Impact of Exercise Training Intensity on Physiological Adaptations and Insulin Resistance in Women with Abdominal Obesity. Healthcare. 2022; 10(12):2533. [DOI:10.3390/healthcare10122533]
28. Evans PL, McMillin SL, Weyrauch LA, Witczak CA. Regulation of skeletal muscle glucose transport and glucose metabolism by exercise training. Nutrients. 2019;11(10):2432. [DOI:10.3390/nu11102432]
29. Gargallo P, Tamayo E, Jiménez-Martínez P, Juesas A, Casana J, Benitez-Martinez JC, et al. Multicomponent and power training with elastic bands improve metabolic and inflammatory parameters, body composition and anthropometry, and physical function in older women with metabolic syndrome: A 20-week randomized, controlled trial. Experimental Gerontology. 2024;185:112340. [DOI:10.1016/j.exger.2023.112340]
30. Kazemi SS, Heidarianpour A, Shokri E. Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial. Lipids in Health and Disease. 2023;22(1):177. [DOI:10.1186/s12944-023-01940-x]
31. Amanat S, Sinaei E, Panji M, MohammadporHodki R, Bagheri-Hosseinabadi Z, Asadimehr H, et al. A randomized controlled trial on the effects of 12 weeks of aerobic, resistance, and combined exercises training on the serum levels of nesfatin-1, irisin-1 and HOMA-IR. Frontiers in physiology. 2020;11:562895. [DOI:10.3389/fphys.2020.562895]
32. Geisler S, Brinkmann C, Schiffer T, Kreutz T, Bloch W, Brixius K. The influence of resistance training on patients with metabolic syndrome-significance of changes in muscle fiber size and muscle fiber distribution. The Journal of Strength & Conditioning Research. 2011;25(9):2598-604. [DOI:10.1519/JSC.0b013e318201bf67]
33. Åkerström T, Stolpe MN, Widmer R, Dejgaard TF, Højberg JM, Møller K, et al. Endurance training improves GLP-1 sensitivity and glucose tolerance in overweight women. Journal of the Endocrine Society. 2022;6(9):bvac111. [DOI:10.1210/jendso/bvac111]
34. Son WM, Park JJ. Resistance band exercise training prevents the progression of metabolic syndrome in obese postmenopausal women. Journal of sports science & medicine. 2021;20(2):291-99. [DOI:10.52082/jssm.2021.291]
35. Schiaffino S, Reggiani C, Akimoto T, Blaauw B. Molecular mechanisms of skeletal muscle hypertrophy. Journal of neuromuscular diseases. 2021;8(2):169-83. [DOI:10.3233/JND-200568]

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