Volume 6, Issue 1 (volume 6, number1 2014)                   IJDO 2014, 6(1): 23-27 | Back to browse issues page

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PhD of Nutrition; Metabolic Disorders Research Center, Departments of Biochemistry and Nutrition. Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Abstract:   (5448 Views)
Objective: The aim of the present study is assessment of insulin resistance (IR) in obese women by TyG-Index and compared with the HOMA-IR index. Materials and Methods: This cross-sectional study was performed on 61 obese women aged 18-45 years. Weights, height, waist circumference (WC) were measured and body mass index (BMI) was calculated and recorded. A sample of fasting serum was collected to determine the glucose, triglyceride, insulin, total cholesterol, HDL-C and LDL-C concentration. HOMA-IR and TyG-Index were calculated as markers of insulin resistance. Results: The mean age of the precipitants was 32.5 ±0.79 years old and the mean weight was 86.0±1.7 Kg. The number of people with IR who determined by HOMA and TyG index were 21(34%) and 36(61%), respectively. There was a significant relationship between HOMA-IR and TyG Index, r= 0.044 (P<0.001). Conclusion: TyG index represents a useful and accessible tool for assessment of IR instead HOMA_IR in Iranian population, but more researches with greater sample size and via gold standard lab test need to evaluate the specificity and sensitivity of this new method.
Keywords: TyG-Index, HOMA-IR, Obesity
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Type of Study: Research | Subject: Special
Received: 2014/12/22 | Accepted: 2014/12/22 | Published: 2014/12/22

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