Volume 2, Issue 1 (1-2010)                   IJDO 2010, 2(1): 12-15 | Back to browse issues page

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Afkhami–Ardekani M, Borgian L, Mohiti -Ardekani J, Chiti Z, Rashidi M, Azod L. The Evaluation of Serum Level of Testosterone and Sex Hormone- Binding Globulin in Men with Type 2 Diabetes. IJDO. 2010; 2 (1) :12-15
URL: http://ijdo.ssu.ac.ir/article-1-20-en.html
Abstract:   (12860 Views)
OBJECTIVE: To evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. MATERIALS AND METHODS: In this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. The two groups were matched for their age and BMI. After complete observation and examination, fasting blood sugar, postprandial blood sugar, total and free testosterone, sex hormone-binding globulin and HbA1c were measured. RESULTS: The mean serum level of total testosterone was 9.65 ± 2.16 mg/dl in diabetic patients and 12.77 ± 3 mg/dl in non-diabetic subjects which was significantly different (P = 0.0001). The mean value of free serum level of testosterone was significantly higher in non-diabetic group (14.96 ± 4.97 mg/dl) in comparison with diabetic group (9.55 ± 8.14 mg/dl, P = 0.0001). CONCLUSION: In this study we found a lower level of total testosterone, free testosterone, and in lesser extent sex hormone-binding globulin in men with type 2 diabetes comparing to non-diabetic men.
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Type of Study: Research | Subject: General
Received: 2011/08/16 | Published: 2010/01/15

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